Wilkerson Gunn

Finally, treatment of mice with the pan-JAK inhibitor, tofacitinib reduced psoriasis-like dermatitis and epidermal pSTAT3 expression. Taken together, STAT3-signaling in keratinocytes rather than T cells was a more important determinant for psoriasis-like dermatitis in a mechanism that involved upstream keratinocyte IL-6R-signaling and downstream…[Read more]